RESPIMAT®

The RESPIMAT® unique mist is an innovative technology which has been designed to overcome some of the challenges of dry powder inhalers (DPIs) and pressurised metered dose inhalers (pMDIs).1-10

RESPIMAT® delivers medication actively, independently from patients’ inhalation force1, unlike DPIs where significant inhalation force is required from the patient to disperse the powder.2-4

Please click here for instructions on how to use SPIOLTO® RESPIMAT®

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Comparative deep lung disposition of RESPIMAT®*

Adapted from reference 9

*In asthma patients - typical scintigraphic images in one patient comparing drug deposition profiles. Mean percentage of the dose deposited in the lungs of 14 asthma patients. For the comparison RESPIMAT® (budesonide) versus TURBOHALER® (budesonide) with a fast inhaled flow rate p<0.001, BECOFORTE® pMDI (beclomethasone dipropionate) p<0.001.

References

  1. Zierenberg B. J Aerosol Med. 1999;12(suppl1):519-524.
  2. Dalby R, et al. lnt J Pharm. 2004;283:1-9.
  3. Janssens W, et al. Eur Respir J. 2008;31 :78-83.
  4. Fernandez Tena A, et al. Arch Bronconeumol. 2012;48:240-246.
  5. Hochrainer D, et al. J Aerosol Med. 2005;18:273-282.
  6. Chapman KR, et al. Eur Respir Rev. 2005;14:117-122.
  7. Newman SP. Eur Respir Rev. 2005;14:1 02-108.
  8. Dalby RN, et al. Med Devices (Auckl). 2011;4:145-155.
  9. Anderson P. lnt J Chron Obstruct Pulmon Dis. 2006;1:251-259.
  10. Pitcairn G, et al. J Aerosol Med. 2005;18:264-272.